BiOligo

Custom RNA Oligos Synthesis

Custom RNA Oligos Synthesis

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Quantity

Scalable Capacity

  • We support synthesis up to gram scale and 120 nt, including multiple modifications on a single oligo.

High Quality, Low Endotoxin  

  • Don't worry about sequence mismatches and incomplete capping, our self-designed synthesis platforms and optimized protocols ensure high-fidelity synthesis and 100% accurate sequence delivery

  • Tired of poor transfection or unexpected toxicity? Our DSL, HPLC, and DHPLC purification options minimize impurities and deliver RNA with purity levels exceeding 98%.

Professional Technical Team

  • New to RNA or need support for your specific project? Just tell us your target gene, species, and application. Our team, backed by over 20 years of RNA experience, will handle the entire process, including sequence design, synthesis, and any required downstream protocols.

Service Details

We offers single-stranded and duplexed RNA synthesis (10–150 nt), including sgRNA, siRNA, miRNA, and crRNA, with customizable options tailored to various experimental needs.

Product Name Purification Quantity QC Lead Time
(Business Day)
RNA Synthesis DSL / HPLC / DHPLC Up to g scale 100% MS & HPLC 7 ~ 10

Modification Types

Fluorescent Group

FAM, BF553, BF647, BF675, BF750, BECU_BF 650, HEX, BF530, ROX, TET, BF390, BF425, BF595, BF633, BF648, BF680, BF405, BF488, JOE, BF549, TAMRA, BF649, BF690, Dylight 755, BF592, Methylene Blue

Quenching Group

BHQ-0, BHQ-1, BHQ-2, BHQ-3, MGB, Eclipse, Dabcyl, SQ1, SQ2

Special Bases

LNA-A/C/G/T, RNA-A/C/G/U, DNA-A/C/G/T, ddC, 2’-O-Methyl, 2’-MOE, 2’-F, 5-Me-dC, rl, dl

Linkers

Spacer 9, Spacer 18, Spacer C3, Spacer C6

Phosphorylation Modifications

PHOS

Thiophosphate Modifications

Phosphorothioate

 

Modified RNA

We provide comprehensive modified RNA synthesis services for lengths ranging from 10 to 150 nucleotides (nt). We can also customize modified synthesis to meet your specific needs, fully accommodating your diverse experimental requirements.

S/N

RNA Synthesis

Specifications

PR005-005

RNA Modified Custom Synthesis (16~30 nt)

5 nmol

PR006-005

RNA Modified Ultra-short Custom Synthesis (10~15 nt)

5 nmol

PR007-005

RNA Modified Long Sequence Custom Synthesis (31~59 nt)

5 nmol

PR008-005

RNA Modified Ultra Long Sequence Custom Synthesis (60~120 nt)

5 nmol


Modification Selections

Type

Modification

5’

Intel

3’

Fluorescent 

groups

FAM

√

 

√

Cy3

√

 

√

Cy5

√

 

√

Cy5.5

√

 

√

Cy7

√

 

√

BECU_BF 650

√

   

HEX

√

 

√

VIC

√

   

ROX

√

 

√

TET

√

   

ATTO 390

√

   

ATTO 425

√

 

√

ATTO 594

√

   

ATTO 633

√

   

ATTO 647N

√

   

ATTO 680

√

   

AF 405

√

   

AF 488

√

 

√

JOE

√

 

√

NED

√

   

TAMRA

√

 

√

CAL Flour Red 635

     

Quasar 670

√

 

√

Quasar 705

√

 

√

Dylight 755

√

   

Texas Red-X

√

 

√

Methylene Blue

√

 

√

Quenched groups

BHQ-0

   

√

BHQ-1

   

√

BHQ-2

   

√

BHQ-3

   

√

MGB

   

√

Eclipse

   

√

Dabcyl

√

 

√

SQ1

   

√

SQ2

   

√

Chemical groups

Biotin

√

 

√

Dual Biotin

√

   

Biotin-teg

√

 

√

Cholesteryl

√

 

√

C6-NH2

√

   

C7-NH2

   

√

DBCO

√

   

Digoxigenin

   

√

Ferrocene

√

 

√

Thiol C6

√

 

√

Thiol Modifier C6-S-S

   

√

Chol

√

 

√

GalNAc

   

√

ZIP4

   

√

Special bases

LNA-A/C/G/T

 

√

 

RNA-A/C/G/U

 

√

 

DNA-A/C/G/T

 

√

 

ddC

   

√

2’-O-Methyl

 

√

 

2’-MOE

 

√

 

2’-F

 

√

 

5-Me-dC

 

√

 

rl

 

√

 

dl

 

√

 

Spacer

Spacer 9

 

√

 

Spacer 18

 

√

√

Spacer C3

 

√

√

Spacer C6

 

√

 

Phosphorylation

PHOS

√

 

√

Thiophosphorylation

Phosphorothioate

√

√

√

 

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