INano™ FAST NANOMEDICINE PREPARATION SYSTEM - Apenzy Biosciences

The unique designed Yortec technology could achieve linear amplification from lab to industry in minimal risk and material cost. Highly customized device and optimized process for multiple nanovehicles include LNP, polymeric nanoparticle, peptide, liposome, etc.

INano™L/L+: Process Optimization 1-120 ml/min

1. 0.4-20 ml/ 0.4-60ml preparation volume 2. Quickly screening formulations (<1 min) 3. Sterile, enzyme-free, and pyrogen-free Cartridge 4. 2 in 1, supports both formulation screening and scale-up process optimization 5. Temperature control 6. Compatible with a wide range of syringes 7. Controlled flow rate (1-120 ml/min), different fluid model cartridges for different delivery systems 8. Reusable cartridge

iNano™P: IND/Clinical/cGMP Manufacturing >48L/h

1. Unique process technology, waste <20 ml 2. Highly automated, capable of automatic exhaust and automatic switching waste liquids 3. Multiple modules are available 4. Complete biocompatibility research data on contact materials 5. Production capacity from 100 ml to several tens of liters 6. Provide equipment GMP validation activities and documentation support 7. Complies with cGMP production requirements and FDA 21CFR Part 11 requirements

iNano™S: cGMP large-scale production >120L/h

1. Complete process solution 2. Production from 2L/min without dilution 3. Highly automated, capable of automatic exhaust and automatic switching waste liquids 4. Optional Henschel alloy mix 5. Complete biocompatibility research data on contact materials 6. Complies with cGMP production requirements and FDA 21CFR Part 11 requirements